ea0029oc7.4 | Adrenal Clinical | ICEECE2012
Satoh F.
, Morimoto R.
, Kudo M.
, Iwakura Y.
, Ono Y.
, Takase K.
, Nakamura Y.
, Sasano H.
, Ito S.
18-Oxocortisol (18-oxoF) is a derivative of cortisol (F) that is produced by aldosterone synthase (CYP11B2), and its clinical usefulness has not been clarified. We prospectively measured 18-oxoF, using highly sensitive liquid chromatography-tandem mass spectrometry (LC/MS/MS), in peripheral plasma of patients with primary aldosteronism (PA) who underwent adrenal venous sampling (AVS) to differentiate aldosterone producing adenoma (APA) from bilateral hyperplasia. The study was...